immunodeficiency due to a late component of complement deficiency
MONDO:0015700Mondo
Findings
No curated finding names immunodeficiency due to a late component of complement deficiency yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A genetic deficiency of any membrane attack complex (MAC, also known as terminal component complex (TCC)) component of the complement system (C5, C6, C7, C8, C9). Deficiencies of the terminal complement pathway results in a predisposition to infections, such as invasive meningococcal disease or disseminated gonococcal infection.
Definition from the Mondo Disease Ontology (MONDO:0015700), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of
Other names
4 names
Resolves to: immunodeficiency due to a late component of complement deficiency
- Also called
- deficiency of complement of terminal pathwayimmunodeficiency due to a C5 to C9 component complement deficiencyimmunodeficiency due to C5 to C9 component complement deficiencyterminal complement pathway deficiency