immunodeficiency 128
MONDO:0975834Mondo
Findings
No curated finding names immunodeficiency 128 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal recessive inheritance
- Onset and course
- Infantile onset
HPO, annotations 2026-09-02
Features
10 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Decreased anti-CD3/28-induced T-cell proliferationHPOHP:0031382
- 4 of 4 reported patients
- Decreased total CD4+ T cell proportionHPOHP:0032218
- 5 of 5 reported patients
- Decreased total T cell countHPOHP:0005403
- 5 of 5 reported patients
- Impaired phytohemagglutinin-induced T lymphocyte transformationHPOHP:0025834
- 4 of 4 reported patients
- Decreased total B cell countHPOHP:0010976
- 3 of 5 reported patients
- Decreased total CD8+ T cell proportionHPOHP:0005415
- 3 of 5 reported patients
- Reduced total natural killer cell countHPOHP:0040218
- 3 of 5 reported patients
- Abnormal gamma-delta T cell proportionHPOHP:0500269
- 0 of 4 reported patients
- Abnormal memory T cell proportionHPOHP:0032182
- 0 of 5 reported patients
- Abnormal naive T cell proportionHPOHP:0031396
- 0 of 5 reported patients
Where it sits
- A kind of