IgG4-related kidney disease
MONDO:0018671Mondo
Findings
No curated finding names IgG4-related kidney disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Features
58 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Increased circulating IgG concentrationHPOHP:0003237
- Very frequent (80% to 99% of cases)
- Increased circulating IgG4 concentrationHPOHP:0032300
- Very frequent (80% to 99% of cases)
- Tubulointerstitial nephritisHPOHP:0001970
- Very frequent (80% to 99% of cases)
- Acute kidney injuryHPOHP:0001919
- Frequent (30% to 79% of cases)
- Antinuclear antibody positivityHPOHP:0003493
- Frequent (30% to 79% of cases)
- Chronic kidney diseaseHPOHP:0012622
- Frequent (30% to 79% of cases)
- Decreased circulating complement C3 concentrationHPOHP:0005421
- Frequent (30% to 79% of cases)
- Decreased circulating complement C4 concentrationHPOHP:0045042
- Frequent (30% to 79% of cases)
- Elevated circulating creatinine concentrationHPOHP:0003259
- Frequent (30% to 79% of cases)
- HematuriaHPOHP:0000790
- Frequent (30% to 79% of cases)
- Increased circulating IgG1 concentrationHPOHP:0032298
- Frequent (30% to 79% of cases)
- ProteinuriaHPOHP:0000093
- Frequent (30% to 79% of cases)
Reported absent (1)
- Sterile pyuriaHPOHP:0100586
Show the remaining 46
- Reduced circulating complement concentrationHPOHP:0004431
- Frequent (30% to 79% of cases)
- Renal insufficiencyHPOHP:0000083
- Frequent (30% to 79% of cases)
- Renal interstitial immunoglobulin depositsHPOHP:0032616
- Frequent (30% to 79% of cases)
- Rheumatoid factor positiveHPOHP:0002923
- Frequent (30% to 79% of cases)
- Abdominal painHPOHP:0002027
- Occasional (5% to 29% of cases)
- Abnormal aortic morphologyHPOHP:0001679
- Occasional (5% to 29% of cases)