idiopathic steroid-sensitive nephrotic syndrome
Findings
No curated finding names idiopathic steroid-sensitive nephrotic syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Steroid-sensitive nephrotic syndrome (SSNS) is a kidney disease defined by selective proteinuria, hypoalbuminaemia and, on renal biopsy, minimal changes without immunoglobulin deposits.
Definition from the Mondo Disease Ontology (MONDO:0019067), read 2026-09-29. CC BY 4.0.
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- LymphedemaHPOHP:0001004
- Very frequent (80% to 99% of cases)
- Nephrotic syndromeHPOHP:0000100
- Very frequent (80% to 99% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- CENPIHGNC:3968
- Limited · Ambry Genetics · X-linked · 2020
Where it sits
- A kind of
- Narrower terms (4)
- idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation
- idiopathic steroid-sensitive nephrotic syndrome with focal segmental hyalinosis
- idiopathic steroid-sensitive nephrotic syndrome with minimal change
- idiopathic steroid-sensitive nephrotic syndrome with secondary steroid resistance