idiopathic localized lipodystrophy
MONDO:0019554Mondo
Findings
No curated finding names idiopathic localized lipodystrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Idiopathic localized lipodystrophy is a rare, acquired, localized lipodystrophy characterized by asymptomatic, well-demarcated, depressed, lipoatrophic lesions of variable size, with normal overlying skin without antecedent inflammation or a known identifiable cause (autoimmune disease, drug injection, injury, etc).
Definition from the Mondo Disease Ontology (MONDO:0019554), read 2026-09-29. CC BY 4.0.
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- LipoatrophyHPOHP:0100578
- Obligate (100% of cases)
- Reduced subcutaneous adipose tissueHPOHP:0003758
- Very frequent (80% to 99% of cases)
- Absence of subcutaneous fatHPOHP:0007485
- Frequent (30% to 79% of cases)
- ErythemaHPOHP:0010783
- Occasional (5% to 29% of cases)
- Hyperpigmentation of the skinHPOHP:0000953
- Occasional (5% to 29% of cases)
- Hypopigmentation of the skinHPOHP:0001010
- Occasional (5% to 29% of cases)
- Inflammatory abnormality of the skinHPOHP:0011123
- Occasional (5% to 29% of cases)
- PruritusHPOHP:0000989
- Occasional (5% to 29% of cases)
- MorpheaHPOHP:0012344
- Very rare (1% to 4% of cases)
- Scaling skinHPOHP:0040189
- Very rare (1% to 4% of cases)
- SclerodermaHPOHP:0100324
- Very rare (1% to 4% of cases)