hypotrichosis-osteolysis-periodontitis-palmoplantar keratoderma syndrome
Findings
No curated finding names hypotrichosis-osteolysis-periodontitis-palmoplantar keratoderma syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hypotrichosis-osteolysis-periodontitis-palmoplantar keratoderma syndrome is an extremely rare ectodermal dysplasia syndrome characterized by hypotrichosis universalis with mild to severe scarring alopecia, acro-osteolysis, onychogryphosis, thin and tapered fingertips, periodontitis and caries leading to premature teeth loss, linear or reticular palmoplantar keratoderma and erythematous, scaling, psoriasis-like skin lesions on arms and legs. Lingua plicata and ventricular tachycardia have also been observed.
Definition from the Mondo Disease Ontology (MONDO:0011884), read 2026-09-29. CC BY 4.0.
Where it sits
Other names
4 names
Resolves to: hypotrichosis-osteolysis-periodontitis-palmoplantar keratoderma syndrome
- Also called
- HOPP syndromehypotrichosis-osteolysis-periodontitis-palmoplantar hyperkeratosis syndromehypotrichosis-striate palmoplantar hyperkeratosis-acroosteolysis-periodontitis syndromehypotrichosis-striate palmoplantar keratoderma-acroosteolysis-periodontitis syndrome