hypothalamic hamartomas with gelastic seizures
MONDO:0019484Mondo
Findings
No curated finding names hypothalamic hamartomas with gelastic seizures yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare cerebral malformation with epilepsy syndrome characterized by early-onset gelastic (i.e. ictal laughter) or dacrystic (i.e., ictal crying) seizures due to non-neoplastic developmental malformation - hypothalamic hamartomas. In many patients, seizures progress to other seizure types including focal and generalized seizures, with concomitant cognitive decline and behavioral disorders. Some patients also present a precocious puberty.
Definition from the Mondo Disease Ontology (MONDO:0019484), read 2026-09-29. CC BY 4.0.
Where it sits
- A kind of