hypertrophic cardiomyopathy 26
Findings
No curated finding names hypertrophic cardiomyopathy 26 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the FLNC gene.
Definition from the Mondo Disease Ontology (MONDO:0014883), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset · Juvenile onset · Young adult onset · Childhood onset
HPO, annotations 2026-09-02
Features
11 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Congestive heart failureHPOHP:0001635
- 6 of 8 reported patients
- Atrial fibrillationHPOHP:0005110
- 4 of 8 reported patients
- Prolonged QTc intervalHPOHP:0005184
- 2 of 8 reported patients
- Right atrial enlargementHPOHP:0030718
- 2 of 8 reported patients
- StrokeHPOHP:0001297
- 2 of 8 reported patients
- Sudden cardiac deathHPOHP:0001645
- 5 of 21 reported patients
- Atrioventricular blockHPOHP:0001678
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- FLNCHGNC:3756
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
- Moderate · Ambry Genetics · Autosomal dominant · 2022
Where it sits
- A kind of
Other names
7 names
Resolves to: hypertrophic cardiomyopathy 26
- Also called
- cardiomyopathy, familial hypertrophic, 26cardiomyopathy, familial hypertrophic, type 26cardiomyopathy, familial restrictive 5CMH26FLNC hypertrophic cardiomyopathyhypertrophic cardiomyopathy caused by mutation in FLNChypertrophic cardiomyopathy type 26