hypertrophic cardiomyopathy 15
Findings
No curated finding names hypertrophic cardiomyopathy 15 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the VCL gene.
Definition from the Mondo Disease Ontology (MONDO:0013200), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset
HPO, annotations 2026-09-02
Features
10 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Apical hypertrophic cardiomyopathyHPOHP:0031992
- 1 of 1 reported patient
- Cardiomyocyte hypertrophyHPOHP:0031319
- 2 of 2 reported patients
- Congestive heart failureHPOHP:0001635
- 2 of 2 reported patients
- Endocardial fibrosisHPOHP:0006685
- 1 of 1 reported patient
- Exertional dyspneaHPOHP:0002875
- 2 of 2 reported patients
- Hyperdynamic left ventricular ejection fractionHPOHP:0034313
- 1 of 1 reported patient
- Hypertrophic cardiomyopathyHPO
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- VCLHGNC:12665
- Limited · Ambry Genetics · Autosomal dominant · 2021
- Limited · Ambry Genetics · Autosomal dominant · 2025
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2023
- Disputed Evidence · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
6 names
Resolves to: hypertrophic cardiomyopathy 15
- Also called
- cardiomyopathy, familial hypertrophic, type 15cardiomyopathy, hypertrophic, 15CMH15hypertrophic cardiomyopathy caused by mutation in VCLhypertrophic cardiomyopathy type 15VCL hypertrophic cardiomyopathy