hypertrichosis-acromegaloid facial appearance syndrome
Findings
No curated finding names hypertrichosis-acromegaloid facial appearance syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hypertrichosis-acromegaloid facial appearance syndrome (HAFF) is a very rare multiple congenital abnormality syndrome manifesting from birth with progressive hypertrichosis congenita terminalis (thick scalp hair extending onto the forehead with generalized increased body hair) associated with a typical acromegaloid facial appearance (thick eyebrows, prominent supraorbital ridges, broad nasal bridge, anteverted nares, long and large philtrum, and prominent mouth with full lips) appearing during childhood. HAFF seems to belong to a spectrum of phenotypes with the clinically overlapping acromegaloid facial appearance syndrome and hypertrichotic osteochondrodysplasia, CantC9 type.
Definition from the Mondo Disease Ontology (MONDO:0019940), read 2026-09-29. CC BY 4.0.
Where it sits
Other names
3 names
Resolves to: hypertrichosis-acromegaloid facial appearance syndrome
- Also called
- haffhypertrichosis-acromegaloid facial features syndromehypertrichosis-coarse face syndrome