hydrocephalus-obesity-hypogonadism syndrome
MONDO:0016346Mondo
Findings
No curated finding names hydrocephalus-obesity-hypogonadism syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
This syndrome is characterized by the association of congenital hydrocephalus, centripetal obesity, hypogonadism, intellectual deficit and short stature.
Definition from the Mondo Disease Ontology (MONDO:0016346), read 2026-09-29. CC BY 4.0.
Features
16 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Cubitus valgusHPOHP:0002967
- Obligate (100% of cases)
- GynecomastiaHPOHP:0000771
- Obligate (100% of cases)
- High, narrow palateHPOHP:0002705
- Obligate (100% of cases)
- HydrocephalusHPOHP:0000238
- Obligate (100% of cases)
- Hypergonadotropic hypogonadismHPOHP:0000815
- Obligate (100% of cases)
- Low posterior hairlineHPOHP:0002162
- Obligate (100% of cases)
- Mild intellectual disabilityHPOHP:0001256
- Obligate (100% of cases)
- Mitral valve prolapseHPOHP:0001634
- Obligate (100% of cases)
- ObesityHPOHP:0001513
- Obligate (100% of cases)
- Short 4th metacarpalHPOHP:0010044
- Obligate (100% of cases)
- Short neckHPOHP:0000470
- Obligate (100% of cases)
- Short statureHPOHP:0004322
- Obligate (100% of cases)
Show the remaining 4
- Abnormality of the hypothalamus-pituitary axisHPOHP:0000864
- Frequent (30% to 79% of cases)
- Absent facial hairHPOHP:0002550
- Frequent (30% to 79% of cases)
- AzoospermiaHPOHP:0000027
- Frequent (30% to 79% of cases)
- Sparse facial hairHPOHP:0007464
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: hydrocephalus-obesity-hypogonadism syndrome
- Also called
- Sengers-Hamel-Otten syndrome