HIV wasting syndrome
Findings
No curated finding names HIV wasting syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Involuntary weight loss of greater than 10 percent associated with intermittent or constant fever and chronic diarrhea or fatigue for more than 30 days in the absence of a defined cause other than hiv infection. A constant feature is major muscle wasting with scattered myofiber degeneration. A variety of etiologies, which vary among patients, contributes to this syndrome. (From Harrison's Principles of Internal Medicine, 13th ed, p1611).
Definition from the Mondo Disease Ontology (MONDO:0005797), read 2026-09-29. CC BY 4.0.
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal gonadotropin-releasing hormone concentrationHPOHP:0500012
- Frequent (30% to 79% of cases)
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- CachexiaHPO · MondoHP:0004326
- Frequent (30% to 79% of cases)
- ImmunodeficiencyHPOHP:0002721
- Frequent (30% to 79% of cases)
- MalabsorptionHPOHP:0002024
- Frequent (30% to 79% of cases)
- MalnutritionHPOHP:0004395
- Frequent (30% to 79% of cases)
- Skeletal muscle atrophy