herpes simplex encephalitis, susceptibility to, 3
Findings
No curated finding names herpes simplex encephalitis, susceptibility to, 3 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A Mendelian susceptibility or predisposition to herpes simplex infection induced encephalitis in which the cause of the diseas is a mutation in the TRAF3 gene.
Definition from the Mondo Disease Ontology (MONDO:0013920), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Childhood onset
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Acute encephalopathyHPOHP:0006846
- 1 of 1 reported patient
- HSV encephalitisHPOHP:0012302
- 1 of 1 reported patient · Childhood onset
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TRAF3HGNC:12033
- Strong · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
3 names
Resolves to: herpes simplex encephalitis, susceptibility to, 3
- Also called
- herpes simplex encephalitis caused by mutation in TRAF3Herpes simplex encephalitis, susceptibility to, type 3TRAF3 herpes simplex encephalitis