hereditary painful callosities
Findings
No curated finding names hereditary painful callosities yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hereditary painful callosities is a nummular palmoplantar keratoderma characterized by the development of painful keratotic lesions over pressure points in hands and feet. A few families have been described. Transmission is autosomal dominant. Successful analgesia can be obtained with tretinoin.
Definition from the Mondo Disease Ontology (MONDO:0007248), read 2026-09-29. CC BY 4.0.
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- PainHPOHP:0012531
- Very frequent (80% to 99% of cases)
- Patchy palmoplantar hyperkeratosisHPOHP:0005588
- Very frequent (80% to 99% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: hereditary painful callosities
- Also called
- keratosis palmoplantaris nummularisPlamoplantar hyperkeratosis nummularisPlamoplantar keratoderma nummularisPPK nummularis