hereditary continuous muscle fiber activity
Findings
No curated finding names hereditary continuous muscle fiber activity yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hereditary continuous muscle fiber activity is a rare, non-dystrophic myopathy characterized by generalized myokymia and increased muscle tone associated with delayed motor milestones, leg stiffness, spastic gait, hyperreflexia and Babinski sign. Symptoms may be worsened by febrile illness or anesthesia.
Definition from the Mondo Disease Ontology (MONDO:0019943), read 2026-09-29. CC BY 4.0.
Features
10 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormality of movementHPOHP:0100022
- Very frequent (80% to 99% of cases)
- Elevated circulating creatine kinase activityHPOHP:0003236
- Very frequent (80% to 99% of cases)
- EMG abnormalityHPOHP:0003457
- Very frequent (80% to 99% of cases)
- Spastic gaitHPOHP:0002064
- Very frequent (80% to 99% of cases)
- Type 1 muscle fiber predominanceHPOHP:0003803
- Very frequent (80% to 99% of cases)
- AtaxiaHPOHP:0001251
- Frequent (30% to 79% of cases)
- Dysarthria
Where it sits
Other names
4 names
Resolves to: hereditary continuous muscle fiber activity
- Also called
- continuous muscle fiber activity hereditarycontinuous muscle fiber activity, hereditarycontinuous muscle fibre activity hereditarycontinuous muscle fibre activity, hereditary