hereditary angioedema type 1
Findings
No curated finding names hereditary angioedema type 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hereditary angioedema type 1 (HAE 1) is a form of hereditary angioedema characterized by acute edema in subcutaneous tissues, viscera and/or the upper airway.
Definition from the Mondo Disease Ontology (MONDO:0015053), read 2026-09-29. CC BY 4.0.
Features
26 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abdominal painHPOHP:0002027
- Very frequent (80% to 99% of cases)
- Abnormal respiratory system morphologyHPOHP:0012252
- Very frequent (80% to 99% of cases)
- Abnormality of metabolism/homeostasisHPOHP:0001939
- Very frequent (80% to 99% of cases)
- Dermatographic urticariaHPOHP:0011971
- Very frequent (80% to 99% of cases)
- Edema of the dorsum of handsHPOHP:0007514
- Very frequent (80% to 99% of cases)
- Facial edemaHPOHP:0000282
- Very frequent (80% to 99% of cases)
- Intestinal edemaHPOHP:0005225
- Very frequent (80% to 99% of cases)
- Laryngeal edemaHPOHP:0012027
- Very frequent (80% to 99% of cases)
- Limbal edemaHPOHP:0025349
- Very frequent (80% to 99% of cases)
- ParesthesiaHPOHP:0003401
- Very frequent (80% to 99% of cases)
- Tongue edemaHPOHP:0040315
- Very frequent (80% to 99% of cases)
- UrticariaHPOHP:0001025
- Very frequent (80% to 99% of cases)
Show the remaining 14
- Abnormality of salivationHPOHP:0100755
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- DysphagiaHPOHP:0002015
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- NauseaHPOHP:0002018
- Frequent (30% to 79% of cases)
- VomitingHPOHP:0002013
- Frequent (30% to 79% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SERPING1HGNC:1228
- Supportive · Orphanet · Autosomal dominant · 2021
Where it sits
Other names
4 names
Resolves to: hereditary angioedema type 1
- Also called
- HAE 1HAE-Ihereditary angioneurotic edema type 1hereditary angioneurotic oedema type 1