hepatic veno-occlusive disease
MONDO:0019514Mondo
Findings
No curated finding names hepatic veno-occlusive disease yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hepatic veno-occlusive disease (hepatic VOD) is a condition resulting from toxic injury to the hepatic sinusoidal capillaries that leads to obstruction of the small hepatic veins.
Definition from the Mondo Disease Ontology (MONDO:0019514), read 2026-09-29. CC BY 4.0.
Features
12 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abdominal painHPOHP:0002027
- Very frequent (80% to 99% of cases)
- AscitesHPOHP:0001541
- Very frequent (80% to 99% of cases)
- Elevated circulating hepatic transaminase concentrationHPOHP:0002910
- Very frequent (80% to 99% of cases)
- HepatomegalyHPOHP:0002240
- Very frequent (80% to 99% of cases)
- Increased body weightHPOHP:0004324
- Very frequent (80% to 99% of cases)
- Increased total bilirubinHPOHP:0003573
- Very frequent (80% to 99% of cases)
- JaundiceHPOHP:0000952
- Very frequent (80% to 99% of cases)
- Renal insufficiencyHPOHP:0000083
- Very frequent (80% to 99% of cases)
- Respiratory failureHPOHP:0002878
- Very frequent (80% to 99% of cases)
- Abnormality of coagulationHPOHP:0001928
- Frequent (30% to 79% of cases)
- Prolonged partial thromboplastin timeHPOHP:0003645
- Frequent (30% to 79% of cases)
- Hepatic encephalopathyHPOHP:0002480
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
- Narrower terms (1)
Other names
4 names
Resolves to: hepatic veno-occlusive disease
- Also called
- Budd Chiari Syndromehepatic Vodliver veno-occlusive diseasesinusoidal obstruction syndrome