heparin-induced thrombocytopenia
MONDO:0018048Mondo
Findings
No curated finding names heparin-induced thrombocytopenia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Heparin-induced thrombocytopenia (HIT) is a drug-induced, immune-mediated prothrombotic disorder associated with thrombocytopenia and venous and/or arterial thrombosis.
Definition from the Mondo Disease Ontology (MONDO:0018048), read 2026-09-29. CC BY 4.0.
Features
15 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Autoimmune thrombocytopeniaHPOHP:0001973
- Very frequent (80% to 99% of cases)
- HypercoagulabilityHPOHP:0100724
- Very frequent (80% to 99% of cases)
- ThromboembolismHPOHP:0001907
- Very frequent (80% to 99% of cases)
- Arterial thrombosisHPOHP:0004420
- Frequent (30% to 79% of cases)
- Deep venous thrombosisHPOHP:0002625
- Frequent (30% to 79% of cases)
- Increased serum serotoninHPOHP:0003144
- Frequent (30% to 79% of cases)
- Venous thrombosisHPOHP:0004936
- Frequent (30% to 79% of cases)
- Cerebral ischemiaHPOHP:0002637
- Occasional (5% to 29% of cases)
- Disseminated intravascular coagulationHPOHP:0005521
- Occasional (5% to 29% of cases)
- Increased inflammatory responseHPOHP:0012649
- Occasional (5% to 29% of cases)
- Mesenteric venous thrombosisHPOHP:0030248
- Occasional (5% to 29% of cases)
- Myocardial infarctionHPOHP:0001658
- Occasional (5% to 29% of cases)
Show the remaining 3
- Pulmonary embolismHPOHP:0002204
- Occasional (5% to 29% of cases)
- StrokeHPOHP:0001297
- Occasional (5% to 29% of cases)
- Abnormal onset of bleedingHPOHP:0040231
- Very rare (1% to 4% of cases)
Where it sits
- A kind of
Other names
5 names
Resolves to: heparin-induced thrombocytopenia
- Also called
- HATheparin-associated thrombocytopeniaheparin-induced thrombocytopenia (disease)heparin-induced thrombocytopenia type 2HIT