hemiparkinsonism-hemiatrophy syndrome
Findings
No curated finding names hemiparkinsonism-hemiatrophy syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hemiparkinsonism-hemiatrophy syndrome is a rare parkinsonian disorder characterized by unilateral body atrophy and slowly progressive, ipsilateral hemiparkinsonian signs (bradykinesia, rigidity, and tremor). Patients typically present with unilateral, action-induced dystonia, in upper or lower limbs, that progresses and becomes bilateral or with tremor which occurs predominantly at rest and progresses to hemiparkinsonism. Scoliosis, scapular winging, raised shoulders, brisk reflexes and extensor plantars are frequently associated.
Definition from the Mondo Disease Ontology (MONDO:0017636), read 2026-09-29. CC BY 4.0.
Features
17 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- BradykinesiaHPOHP:0002067
- Frequent (30% to 79% of cases)
- Brain atrophyHPOHP:0012444
- Frequent (30% to 79% of cases)
- DysarthriaHPOHP:0001260
- Frequent (30% to 79% of cases)
- DystoniaHPOHP:0001332
- Frequent (30% to 79% of cases)
- Generalized hypotoniaHPOHP:0001290
- Frequent (30% to 79% of cases)
- HemiatrophyHPOHP:0100556
- Frequent (30% to 79% of cases)
- Hemifacial atrophyHPO
Show the remaining 5
- TremorHPOHP:0001337
- Frequent (30% to 79% of cases)
- Cerebral cortical hemiatrophyHPOHP:0100308
- Occasional (5% to 29% of cases)
- DepressionHPOHP:0000716
- Occasional (5% to 29% of cases)
- Gait disturbanceHPOHP:0001288
- Occasional (5% to 29% of cases)
- ScoliosisHPOHP:0002650
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: hemiparkinsonism-hemiatrophy syndrome
- Also called
- Hp-HA syndrome