hemifacial hypertrophy
Findings
No curated finding names hemifacial hypertrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Hemifacial hyperplasia is a rare morphological anomaly of the maxillofacial region characterized by unilateral overgrowth of all facial structures (bone, soft tissues, teeth), called true hemifacial hypertrophy, or overgrowth of one or more but not all facial structures, called partial hemifacial hypertrophy. It may be isolated or related to some syndromes (e.g. Beckwith-Wiedemann, Proteus, Klippel-Trenaunay-Weber, McCune-Albright syndrome, Neurofibromatosis type 1). It may be associated with airway obstruction, sensorineural hearing loss or swallowing difficulties.
Definition from the Mondo Disease Ontology (MONDO:0007590), read 2026-09-29. CC BY 4.0.
Features
15 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Hemifacial hypertrophyHPOHP:0005323
- Obligate (100% of cases)
- Facial asymmetryHPOHP:0000324
- Very frequent (80% to 99% of cases)
- Dental malocclusionHPOHP:0000689
- Frequent (30% to 79% of cases)
- Deviated nasal septumHPOHP:0004411
- Frequent (30% to 79% of cases)
- HemimacroglossiaHPOHP:0100875
- Frequent (30% to 79% of cases)
- MacrodontiaHPOHP:0001572
- Frequent (30% to 79% of cases)
- Thick vermilion borderHPO
Show the remaining 3
- Respiratory distressHPOHP:0002098
- Occasional (5% to 29% of cases)
- Unilateral deafnessHPOHP:0009900
- Occasional (5% to 29% of cases)
- Unilateral sensorineural hearing impairmentHPOHP:0025797
- Occasional (5% to 29% of cases)
Where it sits
- A kind of