GRFoma
MONDO:0019955Mondo
Findings
No curated finding names GRFoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
6cm and approximately 1/3 have metastasized at the time of diagnosis. It often co-occurs with Zollinger-Ellison syndrome or multiple endocrine neoplasia type 1 (MEN 1).
Definition from the Mondo Disease Ontology (MONDO:0019955), read 2026-09-29. CC BY 4.0.
Features
38 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Elevated circulating growth hormone concentrationHPOHP:0000845
- Very frequent (80% to 99% of cases)
- Abnormal abdomen morphologyHPOHP:0001438
- Frequent (30% to 79% of cases)
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- Coarse facial featuresHPOHP:0000280
- Frequent (30% to 79% of cases)
- ConstipationHPOHP:0002019
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- Episodic abdominal painHPOHP:0002574
- Frequent (30% to 79% of cases)
- HepatomegalyHPOHP:0002240
- Frequent (30% to 79% of cases)
- Hypoactive bowel soundsHPOHP:0030144
- Frequent (30% to 79% of cases)
- Increased circulating cortisol levelHPOHP:0003118
- Frequent (30% to 79% of cases)
- Nausea and vomitingHPOHP:0002017
- Frequent (30% to 79% of cases)
- Neoplasm of the lungHPOHP:0100526
- Frequent (30% to 79% of cases)
Show the remaining 26
- Neoplasm of the pancreasHPOHP:0002894
- Frequent (30% to 79% of cases)
- Palmoplantar hyperhidrosisHPOHP:0007410
- Frequent (30% to 79% of cases)
- Poor appetiteHPOHP:0004396
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
- Zollinger-Ellison syndromeHPOHP:0002044
- Frequent (30% to 79% of cases)
- Abnormality of the thyroid glandHPOHP:0000820
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: GRFoma
- Also called
- GRF tumorGRF tumourGrowth hormone releasing factor tumorGrowth hormone releasing factor tumour