GPR161-related medulloblastoma predisposition
MONDO:1010204Mondo
Findings
No curated finding names GPR161-related medulloblastoma predisposition yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A predisposition to medulloblastoma, a tumor that originates in the cerebellum and dorsal brainstem, has a peak incidence in childhood, and makes up a large proportion of embryonal brain tumors due to a variation in the GPR161 gene.
Definition from the Mondo Disease Ontology (MONDO:1010204), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- GPR161HGNC:23694
- Strong · ClinGen · Autosomal dominant · 2026
Where it sits
- A kind of