Good syndrome
MONDO:0015696Mondo
Findings
No curated finding names Good syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Good syndrome, also known as thymoma-immunodeficiency, is a very rare acquired immunodeficiency syndrome characterized by the association of thymoma and combined B-cell and T-cell immunodeficiency of adult onset with increased susceptibility to infections.
Definition from the Mondo Disease Ontology (MONDO:0015696), read 2026-09-29. CC BY 4.0.
Features
20 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Decreased circulating immunoglobulin concentrationHPOHP:0004313
- Very frequent (80% to 99% of cases)
- Mediastinal lymphadenopathyHPOHP:0100721
- Very frequent (80% to 99% of cases)
- ThymomaHPOHP:0100522
- Very frequent (80% to 99% of cases)
- Abnormal leukocyte morphologyHPOHP:0001881
- Frequent (30% to 79% of cases)
- BronchiectasisHPOHP:0002110
- Frequent (30% to 79% of cases)
- CoughHPOHP:0012735
- Frequent (30% to 79% of cases)
- DysphagiaHPOHP:0002015
- Frequent (30% to 79% of cases)
- DysphoniaHPOHP:0001618
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- Fatigable weaknessHPOHP:0003473
- Frequent (30% to 79% of cases)
- PtosisHPOHP:0000508
- Frequent (30% to 79% of cases)
- Recurrent skin infectionsHPOHP:0001581
- Frequent (30% to 79% of cases)
Show the remaining 8
- Recurrent urinary tract infectionsHPOHP:0000010
- Frequent (30% to 79% of cases)
- SinusitisHPOHP:0000246
- Frequent (30% to 79% of cases)
- AnemiaHPOHP:0001903
- Occasional (5% to 29% of cases)
- Aplasia/Hypoplasia of the thymusHPOHP:0010515
- Occasional (5% to 29% of cases)
- Diabetes mellitusHPOHP:0000819
- Occasional (5% to 29% of cases)
- DiarrheaHPOHP:0002014
- Occasional (5% to 29% of cases)
Where it sits
Other names
2 names
Resolves to: Good syndrome
- Also called
- thymoma-immunodeficiencythymoma-immunodeficiency syndrome