glucagonoma
MONDO:0019959Mondo
Findings
No curated finding names glucagonoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.
Definition from the Mondo Disease Ontology (MONDO:0019959), read 2026-09-29. CC BY 4.0.
Features
42 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Neoplasm of the pancreasHPOHP:0002894
- Very frequent (80% to 99% of cases)
- Abnormal blistering of the skinHPOHP:0008066
- Frequent (30% to 79% of cases)
- AcanthocytosisHPOHP:0001927
- Frequent (30% to 79% of cases)
- AnorexiaHPOHP:0002039
- Frequent (30% to 79% of cases)
- Chronic fatigueHPOHP:0012432
- Frequent (30% to 79% of cases)
- ConstipationHPOHP:0002019
- Frequent (30% to 79% of cases)
- Diabetes mellitusHPOHP:0000819
- Frequent (30% to 79% of cases)
- DiarrheaHPOHP:0002014
- Frequent (30% to 79% of cases)
- Episodic abdominal painHPOHP:0002574
- Frequent (30% to 79% of cases)
- GlossitisHPOHP:0000206
- Frequent (30% to 79% of cases)
- HepatomegalyHPOHP:0002240
- Frequent (30% to 79% of cases)
- Nausea and vomitingHPOHP:0002017
- Frequent (30% to 79% of cases)
Show the remaining 30
- Necrolytic migratory erythemaHPOHP:0031181
- Frequent (30% to 79% of cases)
- Normochromic anemiaHPOHP:0001895
- Frequent (30% to 79% of cases)
- Poor appetiteHPOHP:0004396
- Frequent (30% to 79% of cases)
- PruritusHPOHP:0000989
- Frequent (30% to 79% of cases)
- Skin rashHPOHP:0000988
- Frequent (30% to 79% of cases)
- StomatitisHPOHP:0010280
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
2 names
Resolves to: glucagonoma
- Also called
- glucagonoma syndromepancreatic glucagonoma