glioma susceptibility 2
MONDO:0013092Mondo
Findings
No curated finding names glioma susceptibility 2 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any malignant glioma in which the cause of the disease is a mutation in the PTEN gene.
Definition from the Mondo Disease Ontology (MONDO:0013092), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late young adult onset
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- MeningiomaHPOHP:0002858
- 1 of 1 reported patient
- OligodendrogliomaHPOHP:0033681
- 1 of 1 reported patient
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- PTENHGNC:9588
- Limited · Ambry Genetics · Autosomal dominant · 2018
Where it sits
- A kind of
Other names
3 names
Resolves to: glioma susceptibility 2
- Also called
- glioma susceptibility type 2malignant glioma caused by mutation in PTENPTEN malignant glioma