generalized eruptive keratoacanthoma
Findings
No curated finding names generalized eruptive keratoacanthoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Generalized eruptive keratoacanthoma (GEKA) is rare variant of keratoacanthoma (KA) that affects the skin and mucous membranes and which is characterized by a sudden generalized eruption of severely pruritic, hundreds to thousands of small follicular papules, often with a central keratotic plug.
Definition from the Mondo Disease Ontology (MONDO:0018471), read 2026-09-29. CC BY 4.0.
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- EctropionHPOHP:0000656
- Frequent (30% to 79% of cases)
- PapuleHPOHP:0200034
- Frequent (30% to 79% of cases)
- PruritusHPOHP:0000989
- Frequent (30% to 79% of cases)
- Abnormal cornea morphologyHPOHP:0000481
- Occasional (5% to 29% of cases)
- ConjunctivitisHPOHP:0000509
- Occasional (5% to 29% of cases)
- DysphagiaHPOHP:0002015
- Occasional (5% to 29% of cases)
- Hoarse voiceHPOHP:0001609
- Occasional (5% to 29% of cases)
- Keratoconjunctivitis siccaHPOHP:0001097
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
4 names
Resolves to: generalized eruptive keratoacanthoma
- Also called
- GEKAgeneralised eruptive keratoacanthomas of Grzybowskigeneralized eruptive keratoacanthomas of GrzybowskiGrzybowski syndrome