gastric mucosal hypertrophy
MONDO:0007652Mondo
Findings
No curated finding names gastric mucosal hypertrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A rare premalignant hyperproliferative gastropathy characterized by massive overgrowth of foveolar cells in the gastric lining, resulting in large gastric folds, and manifesting with epigastric pain, nausea, vomiting, peripheral edema and, less commonly, anorexia and weight loss.
Definition from the Mondo Disease Ontology (MONDO:0007652), read 2026-09-29. CC BY 4.0.
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal gastric mucosa morphologyHPOHP:0004295
- Very frequent (80% to 99% of cases)
- Giant hypertrophic gastritisHPOHP:0005246
- Very frequent (80% to 99% of cases)
- Abdominal painHPOHP:0002027
- Frequent (30% to 79% of cases)
- AstheniaHPOHP:0025406
- Frequent (30% to 79% of cases)
- Helicobacter pylori infectionHPOHP:0005202
- Frequent (30% to 79% of cases)
- HypoalbuminemiaHPOHP:0003073
- Frequent (30% to 79% of cases)
- HypoproteinemiaHPOHP:0003075
- Frequent (30% to 79% of cases)
- MalnutritionHPOHP:0004395
- Frequent (30% to 79% of cases)
- NauseaHPOHP:0002018
- Frequent (30% to 79% of cases)
- Peripheral edemaHPOHP:0012398
- Frequent (30% to 79% of cases)
- VomitingHPOHP:0002013
- Frequent (30% to 79% of cases)
- Weight lossHPOHP:0001824
- Frequent (30% to 79% of cases)
Show the remaining 9
- AnorexiaHPOHP:0002039
- Occasional (5% to 29% of cases)
- DiarrheaHPOHP:0002014
- Occasional (5% to 29% of cases)
- Gastroesophageal refluxHPOHP:0002020
- Occasional (5% to 29% of cases)
- Gastrointestinal hemorrhageHPOHP:0002239
- Occasional (5% to 29% of cases)
- Hypochromic microcytic anemiaHPOHP:0004840
- Occasional (5% to 29% of cases)
- Multiple gastric polypsHPOHP:0004394
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
7 names
Resolves to: gastric mucosal hypertrophy
- Also called
- giant hypertrophic gastritishypertrophic gastritishypertrophic gastropathyhypoproteinemic hypertrophic gastropathyMENETRIER diseaseMénétrier diseaseMenetrier's disease