ganglioneuroma
Findings
No curated finding names ganglioneuroma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood. Ganglioneuroma typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray.
Definition from the Mondo Disease Ontology (MONDO:0005033), read 2026-09-29. CC BY 4.0.
Features
16 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- GanglioneuromaHPOHP:0003005
- Obligate (100% of cases)
- Abnormal mediastinum morphologyHPOHP:0045026
- Frequent (30% to 79% of cases)
- Abnormality of the adrenal glandsHPOHP:0000834
- Frequent (30% to 79% of cases)
- Colorectal polyposisHPOHP:0200063
- Frequent (30% to 79% of cases)
- Multiple intestinal neurofibromatosisHPOHP:0005220
- Frequent (30% to 79% of cases)
- Episodic abdominal painHPOHP:0002574
- Occasional (5% to 29% of cases)
- Functional intestinal obstruction
Show the remaining 4
- Abnormal rectum morphologyHPOHP:0002034
- Very rare (1% to 4% of cases)
- Abnormality of the orbital regionHPOHP:0000315
- Very rare (1% to 4% of cases)
- Central hypoventilationHPOHP:0007110
- Very rare (1% to 4% of cases)
- Gastrointestinal hemorrhageHPOHP:0002239
- Very rare (1% to 4% of cases)
Where it sits
Other names
4 names
Resolves to: ganglioneuroma
- Also called
- ganglioneuroma (disease)ganglioneuroma (Schwannian Stroma-dominant)ganglioneuroma, benignneural Crest tumor, benign