frontotemporal dementia and/or amyotrophic lateral sclerosis 5
MONDO:0030875Mondo
Findings
No curated finding names frontotemporal dementia and/or amyotrophic lateral sclerosis 5 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Late onset · Middle age onset
HPO, annotations 2026-09-02
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Amyotrophic lateral sclerosisHPOHP:0007354
- 9 of 13 reported patients
- Frontotemporal dementiaHPOHP:0002145
- 2 of 13 reported patients
- Atypical behaviorHPOHP:0000708
- DysarthriaHPOHP:0001260
- FasciculationsHPOHP:0002380
- Limb muscle weaknessHPOHP:0003690
- Muscle fibrillationHPOHP:0010546
- Muscle weaknessHPOHP:0001324
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- CCNFHGNC:1591
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
- Limited · ClinGen · Autosomal dominant · 2022
Where it sits
Other names
1 name
Resolves to: frontotemporal dementia and/or amyotrophic lateral sclerosis 5
- Also called
- FTDALS5