focal palmoplantar and gingival keratoderma
Findings
No curated finding names focal palmoplantar and gingival keratoderma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Focal palmoplantar and gingival keratoderma is a very rare form of focal palmoplantar keratoderma characterized by painful circumscribed hyperkeratotic lesions on weight-bearing areas of soles, moderate focal hyperkeratosis of palmar pressure-related areas and an asymptomatic leukokeratosis confined to labial- and lingual- attached gingiva. Additional occasional features may include hyperhidrosis, follicular keratosis and extended oral mucosa involvement.
Definition from the Mondo Disease Ontology (MONDO:0007860), read 2026-09-29. CC BY 4.0.
Features
9 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal fingernail morphologyHPOHP:0001231
- Very frequent (80% to 99% of cases)
- Circumungual hyperkeratosisHPOHP:0008399
- Very frequent (80% to 99% of cases)
- Focal friction-related palmoplantar hyperkeratosisHPOHP:0007497
- Very frequent (80% to 99% of cases)
- Gingival hyperkeratosisHPOHP:0000222
- Very frequent (80% to 99% of cases)
- Gingival overgrowthHPOHP:0000212
- Very frequent (80% to 99% of cases)
- Palmoplantar keratodermaHPOHP:0000982
- Very frequent (80% to 99% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: focal palmoplantar and gingival keratoderma
- Also called
- focal palmoplantar and gingival hyperkeratosis