FLOTCH syndrome
MONDO:0016083Mondo
Findings
No curated finding names FLOTCH syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
FLOTCH syndrome is a rare, genetic, cutaneous disorder characterized by leuchonychia and multiple, recurrent pilar cysts, associated or not with ciliar dystrophy and/or koilonychia. Renal calculi have also been reported.
Definition from the Mondo Disease Ontology (MONDO:0016083), read 2026-09-29. CC BY 4.0.
Features
9 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal eyelash morphologyHPOHP:0000499
- Very frequent (80% to 99% of cases)
- Abnormal eyelid morphologyHPOHP:0000492
- Very frequent (80% to 99% of cases)
- Abnormal nail morphologyHPOHP:0001597
- Very frequent (80% to 99% of cases)
- Inflammatory abnormality of the eyeHPOHP:0100533
- Very frequent (80% to 99% of cases)
- Neoplasm of the skinHPOHP:0008069
- Very frequent (80% to 99% of cases)
- PhotophobiaHPOHP:0000613
- Very frequent (80% to 99% of cases)
- Sparse eyelashesHPOHP:0000653
- Very frequent (80% to 99% of cases)
- BlepharitisHPOHP:0000498
- Frequent (30% to 79% of cases)
- Kidney stoneHPOHP:0000787
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: FLOTCH syndrome
- Also called
- leukonychia totalis-trichilemmal cysts-ciliary dystrophy syndrome