Fliedner-Zweier syndrome
MONDO:0957787Mondo
Findings
No curated finding names Fliedner-Zweier syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Congenital onset · Infantile onset · Childhood onset
HPO, annotations 2026-09-02
Features
36 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Bulbous noseHPOHP:0000414
- 1 of 1 reported patient
- Delayed speech and language developmentHPOHP:0000750
- 7 of 7 reported patients
- EsodeviationHPOHP:0020045
- 1 of 1 reported patient
- Feeding difficultiesHPOHP:0011968
- 1 of 1 reported patient
- Global developmental delayHPOHP:0001263
- 11 of 11 reported patients
- High palateHPOHP:0000218
- 1 of 1 reported patient
- Intellectual disabilityHPOHP:0001249
- 2 of 2 reported patients
- Joint hypermobilityHPOHP:0001382
- 1 of 1 reported patient
- Long philtrumHPOHP:0000343
- 1 of 1 reported patient
- Pes planusHPOHP:0001763
- 1 of 1 reported patient
- Ventricular septal defectHPOHP:0001629
- 3 of 4 reported patients
- SeizureHPOHP:0001250
- 7 of 11 reported patients
Show the remaining 24
- HypotoniaHPOHP:0001252
- 4 of 7 reported patients
- Aggressive behaviorHPOHP:0000718
- 5 of 9 reported patients
- Autistic behaviorHPOHP:0000729
- 5 of 9 reported patients
- Multicystic kidney dysplasiaHPOHP:0000003
- 2 of 5 reported patients
- KyphosisHPOHP:0002808
- 2 of 9 reported patients
- Bicuspid aortic valveHPOHP:0001647
- 1 of 5 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- SCAF4HGNC:19304
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Strong · G2P · Autosomal dominant · 2025
Where it sits
- A kind of