Feingold syndrome
Findings
No curated finding names Feingold syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Feingold syndrome (FS), also known as oculo-digito-esophageal-duodenal (ODED) syndrome, is a rare inherited malformation syndrome characterized by microcephaly, short stature and numerous digital anomalies and is comprised of two subtypes: FS type 1 (FS1) and FS type 2 (FS2). FS1 is by far the most common form while FS2 has only been reported in 3 patients and has the same clinical characteristics as FS1, apart from the absence of gastrointestinal atresia and short palpebral fissures.
Definition from the Mondo Disease Ontology (MONDO:0015267), read 2026-09-29. CC BY 4.0.
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- BrachydactylyHPOHP:0001156
- Very frequent (80% to 99% of cases)
- Clinodactyly of the 5th fingerHPOHP:0004209
- Very frequent (80% to 99% of cases)
- Deviation of the 2nd fingerHPOHP:0009468
- Very frequent (80% to 99% of cases)
- MicrocephalyHPOHP:0000252
- Very frequent (80% to 99% of cases)
- Short palpebral fissureHPOHP:0012745
- Very frequent (80% to 99% of cases)
- Abnormal pinna morphologyHPOHP:0000377
- Frequent (30% to 79% of cases)
Show the remaining 9
- Toe syndactylyHPOHP:0001770
- Frequent (30% to 79% of cases)
- Abnormal vertebral body morphologyHPOHP:0003312
- Occasional (5% to 29% of cases)
- Abnormality of the spleenHPOHP:0001743
- Occasional (5% to 29% of cases)
- Annular pancreasHPOHP:0001734
- Occasional (5% to 29% of cases)
- Duodenal atresiaHPOHP:0002247
- Occasional (5% to 29% of cases)
- Esophageal atresiaHPOHP:0002032
- Occasional (5% to 29% of cases)
Where it sits
- Narrower terms (2)
Other names
12 names
Resolves to: Feingold syndrome
- Also called
- Brunner-Winter syndromedigital anomalies with short palpebral fissures and atresia of esophagus or duodenumdigital anomalies with short palpebral fissures and atresia of oesophagus or duodenumFGLDSFSmicrocephaly-digital anomalies-normal intelligence syndromemicrocephaly-intellectual disability-tracheoesophageal fistula syndromemicrocephaly-oculo-digito-esophageal-duodenal syndrome syndromeMMTMODED syndromeoculo-digito-esophageal-duodenal syndromeODED syndrome