FAS-related autoimmune lymphoproliferative immune disorder
MONDO:1060194Mondo
Findings
No curated finding names FAS-related autoimmune lymphoproliferative immune disorder yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
An autoimmune lymphoproliferative syndrome that results from defective lymphocyte homoestasis, and is caused by variants in the FAS gene. It is characterized by non-malignant lymphoproliferation, autoimmune disease, and lifelong increased risk for both Hodgkin and non-Hodgkin lymphoma.
Definition from the Mondo Disease Ontology (MONDO:1060194), read 2026-09-29. CC BY 4.0.
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- FASHGNC:11920
- Definitive · ClinGen · Semidominant · 2025