familial temporal lobe epilepsy 8
Findings
No curated finding names familial temporal lobe epilepsy 8 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A temporal lobe epilepsy characterized by autosomal dominant inheritance of complex partial seizures with occasional secondary generalization and that has material basis in heterozygous mutation in the GAL gene on chromosome 11q13.
Definition from the Mondo Disease Ontology (MONDO:0014650), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Juvenile onset
HPO, annotations 2026-09-02
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Bilateral tonic-clonic seizure with focal onsetHPOHP:0007334
- 2 of 2 reported patients
- Deja vu auraHPOHP:0012005
- 2 of 2 reported patients
- Focal impaired awareness seizureHPOHP:0002384
- 2 of 2 reported patients · Young adult onset
- Focal aware autonomic seizure with epigastric sensation/nausea/vomiting/other gastrointestinal phenomenaHPOHP:0032785
- 1 of 2 reported patients
- Focal aware cognitive seizure with forced thinkingHPOHP:0032705
- 1 of 2 reported patients
- Focal aware sensory seizure with auditory featuresHPOHP:0032864
- 1 of 2 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- GALHGNC:4114
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2017
Where it sits
- A kind of
Other names
3 names
Resolves to: familial temporal lobe epilepsy 8
- Also called
- epilepsy, familial temporal lobe, type 8ETL8familial temporal lobe epilepsy type 8