familial papillary thyroid carcinoma with renal papillary neoplasia
MONDO:0011578Mondo
Findings
No curated finding names familial papillary thyroid carcinoma with renal papillary neoplasia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Familial papillary thyroid carcinoma with renal papillary neoplasia (fPTC/PRN) is an extremely rare inherited tumor syndrome within the familial nonmedullary thyroid cancer group (fNMTC).
Definition from the Mondo Disease Ontology (MONDO:0011578), read 2026-09-29. CC BY 4.0.
Features
14 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal neck blood vessel morphologyHPOHP:3000037
- Very frequent (80% to 99% of cases)
- Neoplasm of head and neckHPOHP:0012288
- Very frequent (80% to 99% of cases)
- Nodular goiterHPOHP:0005994
- Very frequent (80% to 99% of cases)
- Papillary renal cell carcinomaHPOHP:0006766
- Very frequent (80% to 99% of cases)
- Papillary thyroid carcinomaHPOHP:0002895
- Very frequent (80% to 99% of cases)
- Abnormal lymph node morphologyHPOHP:0002733
- Frequent (30% to 79% of cases)
- Chronic noninfectious lymphadenopathyHPOHP:0002730
- Frequent (30% to 79% of cases)
- GoiterHPOHP:0000853
- Frequent (30% to 79% of cases)
- Breast carcinomaHPOHP:0003002
- Occasional (5% to 29% of cases)
- Chronic lung diseaseHPOHP:0006528
- Occasional (5% to 29% of cases)
- Colon cancerHPOHP:0003003
- Occasional (5% to 29% of cases)
- Recurrent fracturesHPOHP:0002757
- Occasional (5% to 29% of cases)
Show the remaining 2
- Renal cortical adenomaHPOHP:0006735
- Occasional (5% to 29% of cases)
- Renal oncocytomaHPOHP:0011798
- Occasional (5% to 29% of cases)
Where it sits
Other names
1 name
Resolves to: familial papillary thyroid carcinoma with renal papillary neoplasia
- Also called
- PTC-RCC