familial nasal acilia
Findings
No curated finding names familial nasal acilia yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Familial nasal acilia is a rare genetic otorhinolaryngologic disease characterized by respiratory morbidity due to lack of cilia on the respiratory tract epithelial cells. The disease manifests from birth with respiratory distress, neonatal pneumonia, dyspnea, lobar atelectasis and bronchiectasis. Recurrent infections of the upper and lower respiratory tract, chronic humid coughing, and chronic sinusitis, otitis and rhinitis are typical lifelong presenting conditions.
Definition from the Mondo Disease Ontology (MONDO:0019634), read 2026-09-29. CC BY 4.0.
Features
8 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal respiratory motile cilium morphologyHPOHP:0005938
- Frequent (30% to 79% of cases)
- BronchiectasisHPOHP:0002110
- Frequent (30% to 79% of cases)
- Chronic rhinitisHPOHP:0002257
- Frequent (30% to 79% of cases)
- Recurrent upper respiratory tract infectionsHPOHP:0002788
- Frequent (30% to 79% of cases)
- AtelectasisHPOHP:0100750
- Occasional (5% to 29% of cases)
- Chronic sinusitisHPOHP:0011109
- Occasional (5% to 29% of cases)
- Dyspnea