familial cutaneous collagenoma
Findings
No curated finding names familial cutaneous collagenoma yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Familial cutaneous collagenoma is a connective tissue nevus characterized by multiple, flesh-colored asymptomatic nodules distributed symmetrically on the trunk and upper arms (mainly on the upper two-thirds of the back), manifesting around adolescence. The skin biopsy reveals an accumulation of collagen fibers with reduction in the number of elastic fibers. Cardiac anomalies may be observed. Familial cutaneous collagenoma follows an autosomal dominant mode of transmission.
Definition from the Mondo Disease Ontology (MONDO:0007271), read 2026-09-29. CC BY 4.0.
Features
7 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- PapuleHPOHP:0200034
- Very frequent (80% to 99% of cases)
- Skin noduleHPOHP:0200036
- Very frequent (80% to 99% of cases)
- Abnormal skin pigmentationHPOHP:0001000
- Frequent (30% to 79% of cases)
- Angina pectorisHPOHP:0001681
- Occasional (5% to 29% of cases)
- Atrial septal defectHPOHP:0001631
- Occasional (5% to 29% of cases)
- CardiomyopathyHPOHP:0001638
- Occasional (5% to 29% of cases)
- Congestive heart failure
Where it sits
- A kind of