facial onset sensory and motor neuronopathy
Findings
No curated finding names facial onset sensory and motor neuronopathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Facial onset sensory and motor neuronopathy is characterized initially by paraesthesia and numbness in the region of the trigeminal nerve distribution, which later progresses to involve the scalp, neck, upper trunk and upper limbs. Onset of motor manifestations occurs later with cramps, fasciculations, dysphagia, dysarthria, muscle weakness and atrophy. This syndrome has been described in four males and appears to be a slowly progressive neurodegenerative disease.
Definition from the Mondo Disease Ontology (MONDO:0019405), read 2026-09-29. CC BY 4.0.
Features
7 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- DysarthriaHPOHP:0001260
- Very frequent (80% to 99% of cases)
- DysphagiaHPOHP:0002015
- Very frequent (80% to 99% of cases)
- FasciculationsHPOHP:0002380
- Very frequent (80% to 99% of cases)
- Muscle spasmHPOHP:0003394
- Very frequent (80% to 99% of cases)
- Muscle weaknessHPOHP:0001324
- Very frequent (80% to 99% of cases)
- ParesthesiaHPOHP:0003401
- Very frequent (80% to 99% of cases)
- Skeletal muscle atrophy
Where it sits
- A kind of
Other names
1 name
Resolves to: facial onset sensory and motor neuronopathy
- Also called
- FOSMN syndrome