Evans syndrome
Findings
No curated finding names Evans syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Evans syndrome is a rare chronic hematologic disorder characterized by the simultaneous or sequential association of autoimmune hemolytic anemia (AIHA; a disorder in which auto-antibodies are directed against red blood cells causing anemia of varying degrees of severity) with immune thrombocytopenic purpura (ITP; a coagulation disorder in which auto-antibodies are directed against platelets causing hemorrhagic episodes) and occasionally autoimmune neutropenia, in the absence of a known underlying etiology.
Definition from the Mondo Disease Ontology (MONDO:0016030), read 2026-09-29. CC BY 4.0.
Features
13 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Autoimmune hemolytic anemiaHPOHP:0001890
- Obligate (100% of cases)
- Autoimmune thrombocytopeniaHPOHP:0001973
- Obligate (100% of cases)
- Autoimmune neutropeniaHPOHP:0001904
- Very frequent (80% to 99% of cases)
- PetechiaeHPOHP:0000967
- Very frequent (80% to 99% of cases)
- Bruising susceptibilityHPOHP:0000978
- Frequent (30% to 79% of cases)
- DyspneaHPOHP:0002094
- Frequent (30% to 79% of cases)
- EpistaxisHPO
Show the remaining 1
- SyncopeHPOHP:0001279
- Occasional (5% to 29% of cases)
Where it sits
Other names
4 names
Resolves to: Evans syndrome
- Also called
- autoimmune hemolytic anaemia and autoimmune thrombocytopeniaautoimmune hemolytic anemia and autoimmune thrombocytopeniaEvans' syndromeimmune pancytopenia