ethylene glycol poisoning
Findings
No curated finding names ethylene glycol poisoning yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Ethylene glycol poisoning is a rare poisoning resulting in elevated anion gap metabolic acidosis, due to the production of glycolic acid, glyoxylic acid, and oxalic acid by alcohol dehydrogenase (ADH) in the liver when ethylene glycol is metabolized, characterized initially by euphoria, slurred speech, encephalopathy, coma and seizures, and followed by late manifestations such as tachycardia, arrhythmias, myocardial depression, hemodynamic imbalance and, finally, acute renal failure.
Definition from the Mondo Disease Ontology (MONDO:0017861), read 2026-09-29. CC BY 4.0.
Features
44 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Lactic acidosisHPOHP:0003128
- Very frequent (80% to 99% of cases)
- Metabolic acidosisHPOHP:0001942
- Very frequent (80% to 99% of cases)
- AtaxiaHPOHP:0001251
- Frequent (30% to 79% of cases)
- ConfusionHPOHP:0001289
- Frequent (30% to 79% of cases)
- DrowsinessHPOHP:0002329
- Frequent (30% to 79% of cases)
- Elevated serum anion gapHPOHP:0031962
- Frequent (30% to 79% of cases)
- EuphoriaHPO
Show the remaining 32
- VomitingHPOHP:0002013
- Frequent (30% to 79% of cases)
- Abnormal pattern of respirationHPOHP:0002793
- Occasional (5% to 29% of cases)
- Abnormal pupillary light reflexHPOHP:0007695
- Occasional (5% to 29% of cases)
- Addictive alcohol useHPOHP:0030955
- Occasional (5% to 29% of cases)
- Atrial fibrillationHPOHP:0005110
- Occasional (5% to 29% of cases)
- ComaHPOHP:0001259
- Occasional (5% to 29% of cases)
Where it sits
- A kind of