eosinophilic fasciitis
Findings
No curated finding names eosinophilic fasciitis yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Eosinophilic fasciitis is a rare connective tissue disease that is characterized by inflammation and thickening of the fascia, usually associated with peripheral eosinophilia. It presents during adulthood with symmetrical and painful swelling of mainly the extremities that progressively become indurated. Fatigue, disabling cutaneous fibrosis, myositis and arthritis may also be observed.
Definition from the Mondo Disease Ontology (MONDO:0009175), read 2026-09-29. CC BY 4.0.
Features
16 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal eosinophil morphologyHPOHP:0001879
- Very frequent (80% to 99% of cases)
- AcrocyanosisHPOHP:0001063
- Very frequent (80% to 99% of cases)
- CellulitisHPOHP:0100658
- Very frequent (80% to 99% of cases)
- EdemaHPOHP:0000969
- Very frequent (80% to 99% of cases)
- FatigueHPOHP:0012378
- Very frequent (80% to 99% of cases)
- Increased total eosinophil countHPOHP:0001880
- Very frequent (80% to 99% of cases)
- Macule
Show the remaining 4
- FasciitisHPOHP:0100537
- Occasional (5% to 29% of cases)
- MyositisHPOHP:0100614
- Occasional (5% to 29% of cases)
- ParesthesiaHPOHP:0003401
- Occasional (5% to 29% of cases)
- Weight lossHPOHP:0001824
- Occasional (5% to 29% of cases)
Where it sits
Other names
3 names
Resolves to: eosinophilic fasciitis
- Also called
- diffuse fasciitis with eosinophiliaeosinophilic fasciitis (disease)Shulman syndrome