ectopic Cushing syndrome
MONDO:0020527Mondo
Findings
No curated finding names ectopic Cushing syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A form of ACTH-dependent Cushing syndrome caused by excess secretion of ACTH by a benign or, more often, malignant non-pituitary tumor.
Definition from the Mondo Disease Ontology (MONDO:0020527), read 2026-09-29. CC BY 4.0.
Features
81 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Diabetes mellitusHPOHP:0000819
- Very frequent (80% to 99% of cases)
- Fatiguable weakness of proximal limb musclesHPOHP:0030200
- Very frequent (80% to 99% of cases)
- Increased circulating ACTH levelHPOHP:0003154
- Very frequent (80% to 99% of cases)
- Increased circulating cortisol levelHPOHP:0003118
- Very frequent (80% to 99% of cases)
- Increased urinary cortisol levelHPOHP:0012030
- Very frequent (80% to 99% of cases)
- Paradoxical increased cortisol secretion on dexamethasone suppression testHPOHP:0003466
- Very frequent (80% to 99% of cases)
- Abdominal obesityHPOHP:0012743
- Frequent (30% to 79% of cases)
- Abnormal libidoHPOHP:0031845
- Frequent (30% to 79% of cases)
- Abnormality of the cardiovascular systemHPOHP:0001626
- Frequent (30% to 79% of cases)
- AcneHPOHP:0001061
- Frequent (30% to 79% of cases)
- Adrenal hyperplasiaHPOHP:0008221
- Frequent (30% to 79% of cases)
- AmenorrheaHPOHP:0000141
- Frequent (30% to 79% of cases)
Reported absent (2)
- Large sella turcicaHPOHP:0002690
- Pituitary corticotropic cell adenomaHPOHP:0008291
Show the remaining 69
- AnxietyHPOHP:0000739
- Frequent (30% to 79% of cases)
- AstheniaHPOHP:0025406
- Frequent (30% to 79% of cases)
- Atypical behaviorHPOHP:0000708
- Frequent (30% to 79% of cases)
- Bruising susceptibilityHPOHP:0000978
- Frequent (30% to 79% of cases)
- Capillary fragilityHPOHP:0025017
- Frequent (30% to 79% of cases)
- Decreased total eosinophil countHPOHP:0031891
- Frequent (30% to 79% of cases)
Where it sits
- A kind of
Other names
6 names
Resolves to: ectopic Cushing syndrome
- Also called
- adrenocorticotropic hormone secretion syndromeCushing syndrome due to ectopic ACTH secretionectopic ACTH secreting tumorectopic ACTH secreting tumouroccult ectopic ACTH secretionparaneoplastic Cushing syndrome