drug rash with eosinophilia and systemic symptoms
Findings
No curated finding names drug rash with eosinophilia and systemic symptoms yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is a hypersensitivity reaction characterized by a generalized skin rash, fever, eosinophilia, lymphocytosis and visceral involvement (hepatitis, nephritis, pneumonitis, pericarditis and myocarditis) and, in some patients, reactivation of human herpes virus 6.
Definition from the Mondo Disease Ontology (MONDO:0015340), read 2026-09-29. CC BY 4.0.
Features
28 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- AngioedemaHPOHP:0100665
- Very frequent (80% to 99% of cases)
- Cardiac arrestHPOHP:0001695
- Very frequent (80% to 99% of cases)
- ErythemaHPOHP:0010783
- Very frequent (80% to 99% of cases)
- ErythrodermaHPOHP:0001019
- Very frequent (80% to 99% of cases)
- FeverHPOHP:0001945
- Very frequent (80% to 99% of cases)
- Immunologic hypersensitivityHPOHP:0100326
- Very frequent (80% to 99% of cases)
- Infectious encephalitis
Show the remaining 16
- Elevated circulating hepatic transaminase concentrationHPOHP:0002910
- Frequent (30% to 79% of cases)
- Increased total lymphocyte countHPOHP:0100827
- Frequent (30% to 79% of cases)
- Interstitial pneumonitisHPOHP:0006515
- Frequent (30% to 79% of cases)
- Pulmonary infiltratesHPOHP:0002113
- Frequent (30% to 79% of cases)
- Acute hepatic failureHPOHP:0006554
- Occasional (5% to 29% of cases)
- CoughHPOHP:0012735
- Occasional (5% to 29% of cases)
Where it sits
Other names
6 names
Resolves to: drug rash with eosinophilia and systemic symptoms
- Also called
- DHSDRESSDRESS syndromeDrug hypersensitivity syndromedrug reaction eosinophilic systemic syndromeDrug reaction with eosinophilia and Systemic symptoms