drug-induced localized lipodystrophy
Findings
No curated finding names drug-induced localized lipodystrophy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Drug-induced localized lipodystrophy is a rare, acquired, localized lipodystrophy characterized by the appearance of asymptomatic, well-demarcated, variably sized, depressed, lipoatrophic lesions secondary to subcutaneous, intradermic or intramuscular drug injection, including corticosteroids, insulin, human growth hormone and antibiotics. Skin coloration may vary from white or hypopigmented to reddish, pinkish or violaceous. Epidermal atrophy may be also present.
Definition from the Mondo Disease Ontology (MONDO:0019553), read 2026-09-29. CC BY 4.0.
Features
6 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- LipoatrophyHPOHP:0100578
- Obligate (100% of cases)
- Reduced subcutaneous adipose tissueHPOHP:0003758
- Very frequent (80% to 99% of cases)
- Absence of subcutaneous fatHPOHP:0007485
- Frequent (30% to 79% of cases)
- ErythemaHPOHP:0010783
- Occasional (5% to 29% of cases)
- Hyperpigmentation of the skinHPOHP:0000953
- Occasional (5% to 29% of cases)
- Hypopigmentation of the skinHPOHP:0001010
- Occasional (5% to 29% of cases)
Where it sits
- A kind of
Other names
1 name
Resolves to: drug-induced localized lipodystrophy
- Also called
- lipoatrophy caused by injected drug