dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome
Findings
No curated finding names dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
A syndrome is characterized by the association of dilated cardiomyopathy and hypergonadotropic hypogonadism (DCM-HH).
Definition from the Mondo Disease Ontology (MONDO:0008915), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
- Onset and course
- Childhood onset
HPO, annotations 2026-09-02
Features
18 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- CardiomyopathyHPOHP:0001638
- 1 of 1 reported patient
- Finger joint contractureHPOHP:0034681
- 1 of 1 reported patient
- MicrotiaHPOHP:0008551
- 1 of 1 reported patient
- Mitral regurgitationHPOHP:0001653
- 1 of 1 reported patient
- Narrow noseHPOHP:0000460
- 1 of 1 reported patient
- PoikilodermaHPOHP:0001029
- 1 of 1 reported patient
- Poor wound healingHPOHP:0001058
Show the remaining 6
- Dilated cardiomyopathyHPO · MondoHP:0001644
- Very frequent (80% to 99% of cases)
- Hypergonadotropic hypogonadismHPO · MondoHP:0000815
- Very frequent (80% to 99% of cases)
- Polycystic ovariesHPOHP:0000147
- Very frequent (80% to 99% of cases)
- Precocious pubertyHPOHP:0000826
- Very frequent (80% to 99% of cases)
- PtosisHPOHP:0000508
- Very frequent (80% to 99% of cases)
- Wide nasal bridgeHPOHP:0000431
- Very frequent (80% to 99% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- LMNAHGNC:6636
- Supportive · Orphanet · Autosomal recessive · 2021
Where it sits
Other names
3 names
Resolves to: dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome
- Also called
- cardiogenital syndromeMalouf syndromeNajjar syndrome