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Reference

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A reference for what the literature reports. Not medical advice.

Disease

diffuse midline glioma, H3 K27-altered

MONDO:1060171Mondo

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Findings

No curated finding names diffuse midline glioma, H3 K27-altered yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

A diffuse midline glioma characterized by H3 K27 alteration and usually either a histone H3 K27M mutation, an EGFR mutation, or aberrant overexpression of EZHIP. The prognosis is poor.

Definition from the Mondo Disease Ontology (MONDO:1060171), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: diffuse intrinsic pontine glioma
Narrower terms (1): diffuse midline glioma, H3 K27M-mutant

Other names

1 name

Resolves to: diffuse midline glioma, H3 K27-altered

Also called: DMG, H3 K27-altered