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A reference for what the literature reports. Not medical advice.

Disease

diazoxide-resistant focal hyperinsulinism

MONDO:0019265Mondo

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Findings

No curated finding names diazoxide-resistant focal hyperinsulinism yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

Diazoxide-resistant focal hyperinsulism (DRFH) is a form of diazoxide-resistant hyperinsulinism characterized by recurrent episodes of profound hypoglycemia caused by an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia) due to a focal adenomatous hyperplasia of pancreas, that is unresponsive to medical treatment with diazoxide, necessitating complete excision of the focal lesion.

Definition from the Mondo Disease Ontology (MONDO:0019265), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: diazoxide-resistant hyperinsulinism
Narrower terms (2): diazoxide-resistant focal hyperinsulinism due to Kir6.2 deficiency
diazoxide-resistant focal hyperinsulinism due to SUR1 deficiency

Other names

1 name

Resolves to: diazoxide-resistant focal hyperinsulinism

Also called: hyperinsulinemic hypoglycemia, diazoxide-resistant focal form