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A reference for what the literature reports. Not medical advice.

Disease

diazoxide-resistant diffuse hyperinsulinism

MONDO:0015625Mondo

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Findings

No curated finding names diazoxide-resistant diffuse hyperinsulinism yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

Diazoxide-resistant diffuse hyperinsulism (DRDH) is a form of Diazoxide resistant hyperinsulinism characterized by recurrent episodes of profound hypoglycemia caused by an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia) due to diffuse involvement of pancreas that is unresponsive to medical treatment with diazoxide, often necessitating near total/total pancreatectomy.

Definition from the Mondo Disease Ontology (MONDO:0015625), read 2026-09-29. CC BY 4.0.

Where it sits

A kind of: diazoxide-resistant hyperinsulinism
Narrower terms (2): autosomal recessive hyperinsulinism due to Kir6.2 deficiency
autosomal recessive hyperinsulinism due to SUR1 deficiency

Other names

1 name

Resolves to: diazoxide-resistant diffuse hyperinsulinism

Also called: hyperinsulinemic hypoglycemia, diazoxide-resistant diffuse form