diabetes mellitus, transient neonatal, 1
MONDO:0011073Mondo
Findings
No curated finding names diabetes mellitus, transient neonatal, 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- DehydrationHPOHP:0001944
- Very frequent (80% to 99% of cases)
- HyperglycemiaHPOHP:0003074
- Very frequent (80% to 99% of cases)
- HypoinsulinemiaHPOHP:0040216
- Very frequent (80% to 99% of cases)
- Intrauterine growth retardationHPOHP:0001511
- Very frequent (80% to 99% of cases)
- Small for gestational ageHPOHP:0001518
- Very frequent (80% to 99% of cases)
- MacroglossiaHPOHP:0000158
- Frequent (30% to 79% of cases)
- Maturity-onset diabetes of the youngHPOHP:0004904
- Frequent (30% to 79% of cases)
- Transient neonatal diabetes mellitusHPOHP:0008255
- Frequent (30% to 79% of cases)
- Umbilical herniaHPOHP:0001537
- Frequent (30% to 79% of cases)
- Abnormal heart morphologyHPOHP:0001627
- Occasional (5% to 29% of cases)
- Abnormality of limbsHPOHP:0040064
- Occasional (5% to 29% of cases)
- Abnormality of the kidneyHPOHP:0000077
- Occasional (5% to 29% of cases)
Reported absent (1)
- Autoimmune antibody positivityHPOHP:0030057
Show the remaining 9
- Abnormality of the nervous systemHPOHP:0000707
- Occasional (5% to 29% of cases)
- Abnormality of the urinary systemHPOHP:0000079
- Occasional (5% to 29% of cases)
- Failure to thriveHPOHP:0001508
- Occasional (5% to 29% of cases)
- Hearing impairmentHPOHP:0000365
- Occasional (5% to 29% of cases)
- HypothyroidismHPOHP:0000821
- Occasional (5% to 29% of cases)
- HypotoniaHPOHP:0001252
- Occasional (5% to 29% of cases)
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- ZFP57HGNC:18791
- Definitive · G2P · Autosomal recessive · 2025
- Strong · Genomics England PanelApp · Autosomal recessive · 2020
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2022
- Strong · PanelApp Australia · Autosomal recessive · 2025
- Moderate · Ambry Genetics · Autosomal recessive · 2024
Where it sits
- A kind of
Other names
2 names
Resolves to: diabetes mellitus, transient neonatal, 1
- Also called
- diabetes mellitus, transient neonatal 1diabetes mellitus, transient neonatal, type 1